15 Search for Non-Genomic Markers as Puberty Predictors in<i>Bos Indicus</i> Cattle
نویسندگان
چکیده
Abstract Brahman cattle are used for crossbreeding due to their maternal ability, heat, and parasite tolerance. displays delayed attainment of puberty compared with taurine breeds. The objective was identify molecular markers in the blood prepubertal heifers bulls that predict early attainment. We hypothesize Brahmans attains have a metabolite signature differs from animals remain prepubertal. Plasma collected 90 (-90d) 30 (-30d) days prior beginning breeding season 156 yearling 28 bulls. Animals were classified as pubertal (pub) or (prepub) based on reproductive variables such tract score pregnancy insemination scrotal circumference semen quality 48 pub prepub 9 7 submitted quantitative mass spectrometry metabolomics analysis. There clear clustering according status (orthogonal projections latent structures discriminant analysis). Concentrations top three metabolites explaining analyzed by t-tests. As approached maturity, there 3.03-, 11.76- 2.08-fold change (P &lt; 0.0001) concentrations PC ae C42:3, ProBetaine, C42:2 measured at -30 vs. -90 days. Similarly, bulls, HipAcid, C4 SM (OH) C24:1 1.52-, 1.53-, 1.45-fold greater 0.0001), respectively. Comparing prebub d, 1.26- 0.001), 0.62- 0.01) 1.11-fold 0.05) hArg, Putrescine AABA concentrations, Regarding 1.57- 0.01), 1.32- 0.03) 1.15-fold FA(18:1), FA(18:2) DG(16:1_18:2) In conclusion, we discovered potential prediction plasma metabolomic signatures Brahman.
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ژورنال
عنوان ژورنال: Journal of Animal Science
سال: 2023
ISSN: ['0021-8812', '1525-3163', '1525-3015', '1544-7847']
DOI: https://doi.org/10.1093/jas/skad068.028